Vinpocetine is a derivative of vincamine, a key component of the lesser periwinkle plant. Vincamine extracted from the Periwinkle plant, Vinca minor and is an alkaloid consequent from the plant Vinca minor L., a member of the periwinkle family. Research suggests that vinpocetine may improve cognitive performance and short-term memory loss that is sometimes experienced with stress or aging. Animal studies have shown that vinpocetine significantly increases circulatory parameters including total cerebral blood flow. View More Vinpocetine Products
How does Vinpocetine work? Vinpocetine is absorbed from the small intestine and then it is elated to the liver via the portal circulation. From the liver via the systemic circulation, it is distributed to various tissues in the body, as well as the brain. Digestion of vinpocetine is very high when given with food and can be up to about 60% of an ingested dose. On a vacant stomach, digestion of an ingested dose can be as low as 7%. Peak plasma levels are obtained within one to two hours after ingestion. Sufficient metabolism to the inactive apovincaminic acid occurs in the liver. Very low amount of un metabolized vinpocetine are excreted in the urine, the chief way of excretion of apovincaminic acid. Within 24 hours, most of the dose is excreted as this metabolite. The exclusion half-life of vinpocetine following ingestion is one to two hours. What makes Vinpocetine special? Vinpocetine enhances oxygen and glucose uptake from blood by brain neurons, and enhances to increase neuronal ATP bio-energy production, even under conditions of hypoxic (low oxygen). Vinpocetine has been shown that vinpocetine boost circulation in the brain, improves oxygen utilization, dilate blood vessels, make red blood cells more bendable, and inhibit aggregation of platelets. Vinpocetine even has antioxidant properties. Vinpocetine also increases the synthesis of several neurotransmitters that affect critical brain functions such as memory recall, focus and mood. Vinpocetine have calcium-channel blocking activity, as well as voltage-gated sodium channel blocking activity. It has also been inhibit the acetylcholine release evoked by excitatory amino acids and to protect neurons against excitotoxicity. Vinpocetine inhibits a cyclic GMP phosphodiesterase, and it is considered that this inhibition enhances cyclic GMP levels in the vascular smooth muscle, foremost to reduced conflict of cerebral vessels and increase of cerebral flow. Vinpocetine has demonstrated antioxidant activity comparable to that of vitamin E. Vinpocetine is an incredible cognitive enhancer that may enhance with Malfunction of mind or bodys from memory loss to cases of acute strokes. Combine Vinpocetine with Phospholoba Q10, Omega-3 Fish Oils, Flaxseed Oil and Vita-Vitamin for optimal brain health and function. Vinpocetine Benefits: Improves cognitive performance Increases cerebral blood flow Can block the exploit of drugs that dislocate memory Can improve speech mutilation Reduces menopausal symptoms Improves the brain's exploitation of glucose Improves memory Alleviates Disturbance in sleep and several types of sleep malfunction of mind or body's Recommended Dosage: Take a 5 mg capsule once daily or as recommended by your health care provider. In assured cases 10 mg may be more suitable, consult with your doctor. Vinpocetine Cautions: Only for adult use Not for use by pregnant or breastfeeding women. May cause stomach upset if taken on an empty stomach. Individuals using blood-thinning medications, including aspirin, should not use vinpocetine. If you have low blood pressure, have a history of heart problems or strokes; consult your doctor before using this product. |